Venue: Van Swieten Saal of the Medical University of Vienna
Address: Van-Swieten-Gasse 1a, 1090 Vienna, Austria
8:00 am: Registration start
9:00 am: Start of conference and Welcome address
9:10 – 10:30 am: Oral session 1 – supported by Atanis Biotech
9:10 – 9:50 am: Keynote lecture: Stephen Galli: “Mast cells: Why do we have them?”
9:50 – 10:10 am: Plenary Lecture 1: Ashley St. John: “Influence of mast cells on antigen presentation”
10:10 – 10:30 am: Plenary Lecture 2: David Vöhringer: “The role of basophils in skin inflammation and protection against helminths”
10:30 – 11:00 am: Coffee break
11:00 – 12:30 pm: Oral session 2 – supported by BluePrint Medicines
11:00 – 11:20 am: Plenary Lecture 3: Laurent Reber: “Dietary fermentable carbohydrates promote type 2 inflammation”
11:20 – 11:40 am: Plenary Lecture 4: Fang Wang: “Decoding neuro-basophil crosstalk in atopic dermatitis”
11:40 am – 12:00 pm: Plenary Lecture 5: Esther Borges Florsheim: “Beyond anaphylaxis: mast cells as regulators of brain function and behavior”
12:00 – 12:10 pm: Oral abstract 1: Haiyan Chen: “Polyamines regulate mast cell homeostasis by targeting the MAPK signaling pathway”
12:10 – 12:20 pm: Oral abstract 2: Colin Guth: “The neuroendocrine peptide catestatin activates mast cell-expressed Mrgprb2 to promote healing and bacterial clearance in MRSA-infected wounds”
12:20 – 12:30 pm: Oral abstract 3: Marta Chroscik: “Charting the cellular architecture of paediatric cutaneous mastocytosis at single-cell resolution”
12:30 pm – 1:30 pm: Lunch break
1:30 pm – 3:00 pm: Oral session 3 – supported by Celldex Therapeutics
1:30 – 1:40 pm: In memoriam Marcus Maurer (Frank Siebenhaar)
1:40 – 2:00 pm: Plenary Lecture 6: Martin Metz: “Targeting mast cells in urticaria and beyond”
2:00 – 2:20 pm: Plenary Lecture 7: Tibor Keler: “Neutralization of soluble stem cell factor for selective mast cell targeting” (Celldex Therapeutics-sponsor science talk)
2:20 – 2:40 pm: Plenary Lecture 8: Kensuke Miyake: “Basophils in the regulation of skin and lung inflammation”
2:40 – 2:50 pm: Oral abstract 4: Aleksandra Dondalska: “Mast cell dynamics in acute and resolved allergic airway inflammation”
2:50 – 3:00 pm: Oral abstract 5: Paula van Tienen: “Identification of shared regulators of IgE- and MRGPRX2-dependent degranulation in human mast cells”
3:00 – 3:30 pm Coffee break
3:30 pm – 4:35 pm: Oral session 4 – supported by Argenx
3:30 – 3:50 pm: Plenary Lecture 9: Anne Dudeck: “Local and interorgan functions of mast cells in skin inflammation”
3:50 – 4:00 pm: Oral abstract 6: Zou Xiang: “STAP1 negatively regulates IgE‑mediated mast cell activation”
4:00 – 4:10 pm: Oral abstract 7: Ciara Campbell: “Neutrophils bound to mast cell granules induce remote damage during early life allergen-induced lung inflammation”
4:00 – 4:30 pm: Poster flash talks 1-10
4:45– 6:15 pm Poster session 1
Venue: Van Swieten Saal of the Medical University of Vienna
8:00 – 9:00 am: EMBRN General assembly
9:00 – 10:30 am: Oral session 5 – Joint session with the International Eosinophil Society (IES) – supported by AstraZeneca
9:00 – 9:10 am: Introduction of the EMBRN/IES partnership
9:10 – 9:30 am: Plenary Lecture 10: Ariel Munitz: “Cellular and Molecular Mechanisms of Eosinophilic Gastrointestinal Diseases”
9:30 – 9:50 am: Plenary Lecture 11: Jenny Hallgren-Martinson: “The Role of IL 5 in Mast Cell Biology: Does It Matter?”
9:50 – 10:10 am: Plenary Lecture 12: Nicola Diny: “Eosinophil plasticity in the context of tissue adaptation”
9:30 – 10:10 am: Plenary Lecture 13: Joseph Jorssen: “Single-cell omics identify eosinophil development and the role of IL-5 in lineage transit amplification”
10:30 – 11:00 am: Coffee break
11:00 – 12:30 pm: Oral session 6 – supported by Genoskin
11:00 – 11:20 am: Plenary Lecture 14: Sabine Altrichter: “Blood, sweat and mastcells – What we know about the pathophysiology of cholinergic urticaria”
11:20 – 11:40 am: Plenary Lecture 15: Nicolas Gaudenzio: “Fetal origins of pediatric eczema and more...”
11:40 am – 12:00 pm: Plenary Lecture 16: Tim Lämmermann: “Mechanisms of Mast Cell Motility: Cytoskeletal Dynamics and Microenvironmental Crosstalk”
12:00 – 12:10 pm: Oral abstract 8: Elin Rönnberg Höckerlind: “IL-33 reshape cell surface receptor expression on Human Lung Mast Cells”
12:10 – 12:20 pm: Oral abstract 9: Jesus Lopez Castillo: “Role of Mast Cells in the neuroinflammation induced by excitotoxic damage in the mice striatum: cytokine production and degradation of perineuronal networks”
12:20 – 12:30 pm: Oral abstract 10: Yi-Kui Xiang: “IgE-anti-TPO assay for diagnosing autoallergic chronic spontaneous urticaria: A cross-sectional, multicenter VANGUARD study”
12:30 pm – 1:30 pm: Lunch break
1:30 pm – 3:00 pm: Oral session 7 – supported by Novartis
1:30 – 1:50 pm: Plenary Lecture 17: Sebastien Talbot: “Pain neurons control allergic inflammation”
1:50 – 2:10 pm: Plenary Lecture 18: Alexander Eggel: “Translational Applications of the Hoxb8 Mast Cell Progenitor Platform”
2:10 – 2:20 pm: Oral abstract 11: Xiaolei Su: “Engineering mast cells to target solid tumors”
2:20 – 2:30 pm: Oral abstract 12: Songmin Ying: “IL-5 CAR-T Cell Therapy: A Novel Targeted Approach for Eosinophil-Associated Disorders”
2:30 – 2:40 pm: Oral abstract 13: Taras Barnofskyi: “Intestinal IL-33-Dependent IgE Induction Aggravates Liver Disease in an FcεRIα–Mediated Manner”
2:40 – 2:50 pm: Oral abstract 14: Gyeongseo Suk: “SelO controls mast cell effector function through AMPylation-dependent regulation of granule biogenesis”
2:50 – 3:00 pm: Oral abstract 15: Lea Madeleine Schmitter: “Ingestion of mast cell granules boosts macrophages and drives atypical programming”
3:00 – 3:30 pm Coffee break
3:30 pm – 4:35 pm: Oral session 8 – supported by Telios Pharma
3:30 – 3:50 pm: Plenary Lecture 19: Xiaoyu Hu: “Local and interorgan functions of mast cells in skin inflammation”
3:50 – 4:00 pm: Oral abstract 16: Regis Joulia: “Single-cell spatial chart of the airway wall reveals mast cell interactions in health and asthma”
4:00 – 4:10 pm: Oral abstract 17: Jelle Folkerts: “SARS-CoV-2 fragments activate human mast cells through MRGPRX2”
4:00 – 4:30 pm: Poster flash talks 1-10
4:45– 6:15 pm Poster session 2
7:30 pm – 12:00 am Gala dinner (supported by the City of Vienna)
7:00 pm: Doors open
7:30 pm: Welcome note by the Mayor of Vienna
Venue: Wiener Rathauskeller (room: Rittersaal) in the Vienna City Hall
Address: Rathausplatz 1, 1010 Vienna, Austria
https://maps.app.goo.gl/XZnzYfUbKSvZDu7x8
Venue: Van Swieten Saal of the Medical University of Vienna
9:00 – 10:30 am: Oral session 9 – supported by Ceva
9:00 – 9:20 am: Plenary Lecture 20: Cecilia Andersson: “Illuminating Mast Cell Diversity: Novel Imaging Insights from the Human Lung”
9:20 – 9:40 am: Plenary Lecture 21: Adrian Piliponsky: “Solute Carrier Proteins as Architects of Mast Cell Function”
9:40 – 9:50 am: Oral abstract 18: Nicolas Charles: “A skin mast cell-basophil crosstalk promotes lupus-like photosensitivity”
9:50 – 10:00 am: Oral abstract 19: Tamara Haque: “TGFb Promotes Mast Cell Effector Function by Targeting Bruton's Tyrosine Kinase”
10:00 – 10:10 am: Oral abstract 20: Nana Shi: “A novel hollow microneedle platform for efficient and minimally invasive sampling of dermal interstitial fluid reveals tissue-specific biomarkers”
10:10 – 10:20 am: Oral abstract 21: Sibilė Šinkūnaitė: “Transcriptomic analysis of anti-IgE activated degranulated and non-degranulated basophils”
10:20 – 10:30 am: Oral abstract 22: Mikael Adner: “Selective KIT Inhibition Reveals Mast Cells as Key Drivers of Allergic Asthma Pathogenesis”
10:30 – 11:00 am: Coffee break
11:00 – 12:20 pm: Oral session 10 – supported by Cogent Biosciences
11:00 – 11:20 am: Plenary Lecture 22: Mrinmoy Das: “Basophils in Skin-Gut Crosstalk: Bridging Atopic Dermatitis and Food Allergy.”
11:20 – 11:30 am: Oral abstract 23: Teal Hallstrand: “Mast cell progenitors are increased in the airways in asthma in association with airway dysfunction and T2 endotype.”
11:30 – 11:40 am: Oral abstract 24: Manuel Stecher: “Mitochondrial fusion mediator OPA1 regulates the maintenance of mast cell homeostasis”
11:40 – 11:50 am: Oral abstract 25: Charlotte Hateb: “Development of an mRNA vaccine encoding the allergen Bet v 1 to treat birch pollen allergy”
11:50 am – 12:00 pm: Oral abstract 26: Charlotte Hateb: “Development of an mRNA vaccine encoding the allergen Bet v 1 to treat birch pollen allergy”
12:00 – 12:10 pm: Oral abstract 27: Daniel Ivanusic: “Capicua acts as a positive regulator of granule-associated mediators in Human Skin Mast cells”
12:10 – 12:20 pm: Oral abstract 28: Konstantinos Katsoulis Dimitriou: “Mast cells initiate lymphocyte egress from distant lymph nodes upon skin inflammation via a RANKL–sphingosine-1-phosphate axis”
12:20 pm – 1:00 pm: Outlook to EMBRN 2028 and Farewell
1:00 pm: End of Conference