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Thaïs Topakian

  1. Universitätsklinik für Innere Medizin I
  2. Unsere Klinischen Abteilungen
  3. Onkologie
  4. Mitarbeiter:innen
  5. Wissenschaftliches Team
  6. Thaïs Topakian

Thaïs Topakian, MSc

wissenschaftl. Mitarbeiterin

Medizinische Universität Wien
Universitätsklinik f. Innere Medizin I
Klinische Abteilung für Onkologie
Währinger Gürtel 18-20
1090 Wien

T: +43 (0)1 40 400 – 73 790
E-Mail: thais.topakian@meduniwien.ac.at

Laufbahn

11/2022 – present Senior Scientist Position in the group of Ap. Prof. Priv.-Doz. Dr. Gerwin Heller, Division of Oncology, Department of Medicine I, Medical University of Vienna
07/2021 – 10/2022 Senior Scientist Position in the group of Dr. med. univ. PhD Maximilian Marhold, Division of Oncology, Department of Medicine I, Medical University of Vienna
03/2019 – 06/2020 Research Assistant Position in the group of Dr. med. univ. PhD Maximilian Marhold, Division of Oncology, Department of Medicine I, Medical University of Vienna
01/2018 – 02/2019 Research Assistant Position in the group of Univ.-Prof. Dr. Sabine Zöchbauer-Müller, Department of Medicine I, Division of Oncology, Medical University of Vienna
07/2017 – 12/2017 Research Assistant Position in the group of Assoc. Prof. Priv.-Doz. Dr. Christoph Steininger, Department of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna
10/2013 – 12/2014 Master Thesis „Methylome and Transcriptome Analyses in MO7e and MO7e 210 cells”, supervised by Univ.-Prof. Dr. Sabine Zöchbauer-Müller, Department of Medicine I, Division of Oncology, Medical University of Vienna
03-04/2012 Internship “Effects of UV irradiation on RNA Pol II and splicing patterns in Physcomitrella patens”, supervised by Ao. Univ.-Prof. Mag. Dr. rer. nat. Andrea Barta, Max F. Perutz Laboratories
09/2015 Master Degree
2012 – 2015 Master Studies Genetics and Developmental Biology
09/2012 Bachelor Degree Biology

Publications

ORIGINAL, PEER-REVIEWED RESEARCH PUBLICATIONS

Altenberger, C., G. Heller, B. Ziegler, E. Tomasich, M. Marhold, T. Topakian, L. Mullauer, P. Heffeter,

G. Lang, A. End-Pfutzenreuter, B. Dome, B. M. Arns, W. Klepetko, C. C. Zielinski, and S. Zöchbauer-Müller. "Spag6 and L1td1 Are Transcriptionally Regulated by DNA Methylation in Non-Small Cell Lung Cancers." Mol Cancer 16, no. 1 (Jan 5 2017): 1.  https://dx.doi.org/10.1186/s12943-016-0568-5.

Bilgilier, C., M. Schneider, K. Kuhrer, N. Kilb, R. Hartl, T. Topakian, M. T. Kastner, T. Herz, C. S. Nelson,

S. R. Permar, G. Roth, and C. Steininger. "Heterosubtypic, Cross-Reactive Immunity to Human Cytomegalovirus Glycoprotein B." Clin Exp Immunol (Apr 8 2022).  https://dx.doi.org/10.1093/cei/uxac031.

Heller, G., C. Altenberger, I. Steiner, T. Topakian, B. Ziegler, E. Tomasich, G. Lang, A. End- Pfutzenreuter, S. Zehetmayer, B. Dome, B. M. Arns, W. Klepetko, C. C. Zielinski, and S. Zöchbauer-Müller. "DNA Methylation of Microrna-Coding Genes in Non-Small-Cell Lung Cancer Patients." J Pathol 245, no. 4 (Aug 2018): 387-98.  https://dx.doi.org/10.1002/path.5079.

Heller, G., A. Rommer, K. Steinleitner, J. Etzler, H. Hackl, P. Heffeter, E. Tomasich, M. Filipits, B. Steinmetz, T. Topakian, S. Klingenbrunner, B. Ziegler, A. Spittler, S. Zöchbauer-Müller, W. Berger, and R. Wieser. "Evi1 Promotes Tumor Growth Via Transcriptional Repression of Ms4a3." J Hematol Oncol 8 (Mar 21 2015): 28. https://dx.doi.org/10.1186/s13045-015-0124-6

Heller, G., T. Topakian, C. Altenberger, S. Cerny-Reiterer, S. Herndlhofer, B. Ziegler, P. Datlinger, K. Byrgazov, C. Bock, C. Mannhalter, G. Hormann, W. R. Sperr, T. Lion, C. C. Zielinski, P. Valent, and S. Zöchbauer-Müller. "Next-Generation Sequencing Identifies Major DNA Methylation Changes During Progression of Ph+ Chronic Myeloid Leukemia." Leukemia 30, no. 9 (Sep 2016): 1861-8. https://dx.doi.org/10.1038/leu.2016.143.

Marhold, M., T. Topakian, H. Agis, R. Bartsch, A. S. Berghoff, T. Brodowicz, T. Fuereder, A. Ilhan- Mutlu, B. Kiesewetter, M. Krainer, G. J. Locker, C. Marosi, G. Prager, M. Schmidinger, C. Thallinger, S. Zöchbauer-Müller, M. Raderer, M. Preusser, and W. Lamm. "Thirteen-Year Analyses of Medical Oncology Outpatient Day Clinic Data: A Changing Field." ESMO Open 5, no. 5 (Oct 2020): e000880. https://dx.doi.org/10.1136/esmoopen-2020-000880.

Marhold, M., S. Udovica, T. Topakian, P. Horak, R. Horvat, E. Tomasich, G. Heller, and M. Krainer. "Malat1 Fusions and Basal Cells Contribute to Primary Resistance against Androgen Receptor Inhibition in Tramp Mice." Cancers (Basel) 14, no. 3 (Jan 31 2022).  https://dx.doi.org/10.3390/cancers14030749.

Tomasich, E., T. Topakian, G. Heller, S. Udovica, M. Krainer, and M. Marhold. "Loss of Hcrp1 Leads to Upregulation of Pd-L1 Via Stat3 Activation and Is of Prognostic Significance in Egfr- Dependent Cancer." Transl Res 230 (Apr 2021): 21-33.  https://dx.doi.org/10.1016/j.trsl.2020.11.005.

 

SHORT REVIEWS

Sarcopenia in cancer – a focus on elderly cancer patients. Marhold M, Topakian T, Unseld M, memo. 2020. https://doi.org/10.007/s12254-020-00637-6.

Homologous repair deficiencies and current insights in clinical evaluation of PARP inhibitors in prostate cancer. Marhold M, Topakian T. memo. 2020. https://doi.org/10.007/s12254-020-  00599-9.